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However, in HAND, conventional anatomicMRI is nonspecific, usually showing only cortical and sub-cortical atrophy with scattered, punctate T2 hyperintenseabnormalities. Rates among dermatology patients (9% to 15%) and cos-metic surgery patients (7% to 8%) are signi?cantly higher. The repeated open-ing and closing of the alveoli (atelectrauma) athigh pressures (barotrauma) and high volumes(volutrauma) in the context of high concentra-tions of oxygen (chemotrauma) caused cysticand ?brotic changes within the neonatal lung.Coupled with increased risks of infection andin? ammation (biotrauma), this led to the devel-opment of BPD

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